NFL Week 16 Predictions: The Home Stretch

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Greetings, my loyal readers.

Due to the holiday season and having the task of cleaning up the entire house for my family, this week’s edition of my predictions will be shorter. Basically, there won’t be any must-start players and there will just be a brief analysis for the select, marquee matchups.

After careful thought, this year has been a whirlwind with everything that has gone on. As Christmas and the new year approach, I decided that it would be necessary to spend the time with the people I love.

Ultimately, I hope to enjoy this break with some great company and some even better football action.

Enjoy the holiday festivities and happy reading!

Last Week’s (Week 15) Pick Record: 8-8

My Overall 2021-22 Pick Record: 137-87

Note: All betting information comes from BetMGM (

Must-Watch Week 16 Matchups

San Francisco 49ers (8-6) vs. Tennessee Titans (8-6)

Time/Channel: 12/23/21 @ 8:20 PM on NFL Network

Spread: San Francisco (-3)

Tennessee looks like a shell of themselves with their prime superstar player sidelined. RB Derrick Henry isn’t expected to make a return this week, which means San Francisco can continue their defensive dominance on the line of scrimmage and attack QB Ryan Tannehill all night long. Side note – WR Deebo Samuel will score again (maybe twice).

My Prediction: San Francisco defeats Tennessee, 27-20

Cleveland Browns (7-7) vs. Green Bay Packers (11-3)

Date/Time/Channel: 12/25/21 @ 4:30 PM on FOX

Spread: Green Bay (-7.5)

Cleveland’s defense is way too good to allow a blasting by Green Bay. I think DE Myles Garrett and company can hold QB Aaron Rodgers below twenty-five points. However, Cleveland has lost their symphonic offensive production, even with both running backs (Chubb and Hunt) active. The Browns simply won’t score enough to keep pace, virtually ending their postseason hopes in the process.

My Prediction: Green Bay defeats Cleveland, 23-16

Indianapolis Colts (8-6) vs. Arizona Cardinals (10-4)

Time/Channel: 12/25/21 @ 8:15 PM on 

Spread: Arizona (-1)

As soon as I thought Arizona was untouchable, they lose to the Detroit Lions. This home game may get QB Kyler Murray back on track, but Indianapolis is probably the hottest team in football. With the way RB Jonathan Taylor and the Colts are dictating game flow, it seems hard to pick against them until some team stops Taylor’s MVP-like run of production. 

My Prediction: Indianapolis defeats Arizona, 27-24

Baltimore Ravens (8-6) vs. Cincinnati Bengals (8-6)

Date/Time/Channel: 12/26/21 @ 1:00 PM on CBS

Spread: Cincinnati (-3)

The winner of this game is likely the winner of the division, so it’s all on the line. QB Lamar Jackson should be available, but recovering from a bone bruise, he may lose some of his mobility. With how stingy DE Trey Hendrickson and the Cincinnati front have been, Jackson will have his work cut out for him. He leads the Ravens close to victory, but QB Joe Burrow counters and proves his team is more than ready to take the next step.

My Prediction: Cincinnati defeats Baltimore, 30-23

Buffalo Bills (8-6) vs. New England Patriots (9-5)

Time/Channel: 12/26/21 @ 1:00 PM on CBS

Spread: New England (-2.5)

The long-awaited rematch between the two AFC East leaders. While more points should be scored in this one, it’s hard to tell. Both defenses have been tremendous this year, but the Bills haven’t looked the same without CB Tre’Davious White locking down half of the field. White played in the first matchup, so rookie QB Mac Jones won’t have to worry this time. This dynamic dominates the game, as Jones likely secures his OROY award by beating the Bills twice in a season and clinching the AFC East.

My Prediction: New England defeats Buffalo, 24-21

My Week 16 Quick Picks:

Detroit defeats Atlanta (-5.5), 18-14

Los Angeles (N) (-3) defeats Minnesota, 27-20

New York (A) defeats Jacksonville (-1), 35-31

New York (N) defeats Philadelphia (-10), 21-18

Los Angeles (A) (-9.5) defeats Houston, 34-21

Tampa Bay (-10) defeats Carolina, 24-10

Las Vegas (-1.5) defeats Denver, 17-10

Seattle (-6.5) defeats Chicago, 24-17

Kansas City (-7.5) defeats Pittsburgh, 31-21

Dallas (-10.5) defeats WFT, 28-24

New Orleans (-3) defeats Miami, 27-21

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Gavin Smith

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